Commercial Properties to Rent in Marylebone (London)

London Medical to Rent - Marylebone, City of Westminster

86 Harley Street offers period features, excellent natural light, a manned reception, and a shared waiting room. The Grade II listed building now offers a 588-square-foot medical suite on the first floor. This one-room suite has been newly redecorated. The Howard de Walden Estate sits at the heart of central London, one of the world’s best-connected cities – within easy reach of several airports, the St. Pancras Eurostar terminal, and numerous mainline and underground stations.

Property Type:

Office

Date on Market:

08/04/2025

London Office to Rent - Marylebone, City of Westminster

This 556-square-foot, first-floor office has been recently refurbished and comprises two rooms. Occupants also enjoy shared tea point facilities and access to an outdoor terrace. This character building is situated on the south side of Devonshire Street, at the junction with Harley Street. Regent's Park and Oxford Circus stations are in proximity. The area is very well-served by the restaurants and shopping facilities of Marylebone Village.

Date on Market:

03/04/2025

London Office to Rent - Marylebone, City of Westminster

Recently refurbished and located off Marylebone Lane, 2 Bentinck Mews is ready for immediate occupancy. Arranged over three floors, this thoughtfully designed workspace by architecture firm Urban Mesh blends modern functionality with charming original features. The fully fitted space is light-filled, open, and welcoming, offering a balance of professionalism and comfort. Unique touches such as restored exterior tiling, exposed concrete, brickwork, and a secret wood-panelled meeting room all add character. The building is full of a curated colour palette, textured furnishings, and smart fittings. The building also benefits from new LED lighting, energy-efficient Daikan HVAC, a VRV air source heat pump, a green roof, and an EPC A rating. Designed to inspire, this office offers something refreshingly bold and creative for businesses looking to stand out in the Marylebone market. 2 Bentinck Mews is in the heart of Marylebone Village, opening up a world of amenities from the doorstep. Occupants will have their pick of premier restaurants like The Cavendish or Lina Stores, upscale hotels, convenient leisure facilities, and beloved local bars, such as The Coach Makers Arms Pub. Furthermore, transport connections are close at hand, with Bond Street station a four-minute walk away, offering fast access across London.

Date on Market:

22/10/2025

London Office / Medical to Rent - Marylebone, City of Westminster

The 1,479-square-foot space comprises three consulting rooms and a kitchenette on the lower ground floor. There is also access to shared WCs and a shared waiting room on the ground floor. The Harley Street Health District is a community of Marylebone-based hospitals, clinics, and specialists, renowned for their outstanding patient care, pioneering treatments, and use of cutting-edge technologies. Combined with the convenience of Marylebone, this location places users among leading healthcare professionals.

Property Type:

Office

Date on Market:

08/04/2025

London Medical to Rent - Marylebone, City of Westminster

11 Devonshire Place has undergone a comprehensive refurbishment and now offers approximately 2,034 square feet of high-quality accommodation arranged across the ground and first floors. Finished to an excellent standard throughout, the building blends period character with modern functionality and has been thoughtfully configured to support professional medical use. The property benefits from seven well-proportioned consulting rooms, a kitchenette, two WCs, a shower facility, air conditioning, and a lift. An external extension further enhances the building’s flexibility, providing a self-contained staff area that could also serve as an ancillary or support space. The building is situated within the heart of the prestigious Harley Street Medical Area, the largest collection of private healthcare professionals in Europe. The area has been pioneering healthcare since the mid-19th century, and remains one of the world’s leading destinations for medical practitioners. Located in Marylebone, the surrounding neighbourhood offers a mix of medical, office, retail, and residential occupiers. Marylebone Village provides an array of restaurants, cafés, and shops, alongside hotels and gyms, while Regent’s Park, offering 395 acres of parkland and extensive leisure facilities, is just a short walk away. Connectivity is excellent, with Regent's Park and Great Portland Street Underground stations both within easy walking distance, and Marylebone Station also close by, ensuring convenient access for patients, staff, and visitors alike.

Property Type:

Office

Date on Market:

10/06/2024

London Office to Rent - Marylebone, City of Westminster

51 Welbeck Street’s lower ground level provides a surprisingly bright and spacious office space for teams of 20+. Encompassing the entire floor, your new office is equipped with a large boardroom, three private offices, a storage cellar, kitchenette, plus room for over 15 open plan desks. Occupiers benefit from an on-site staffed reception, end of trip facilities, and a reputable address, surrounded by amazing local amenities. Your commute is simple too, with access to some of London’s major underground stations, all within a 5-15 minute walk.

Date on Market:

25/03/2026

London Retail to Rent - Marylebone, City of Westminster

The property comprises a mixed-use building with retail space arranged over the basement and ground-floor with offices on the above three floors. The property is prominently located on the south side of Marylebone Lane at its junction with Marylebone High Street thus clearly visible from the High Street. The street benefits from the enhanced shared road/pedestrianised paving which has vastly improved the retail experience forming part of Howard De Walden’s investment linking Wigmore Street with Marylebone High Street. It is a much sought-after location with a wide variety of high-quality dynamic retailers and restaurants close by including a number of independent brands. Nearby traders include le Relais de Venise L’Entrecote, Ottolenghi and Caldesi with the unit facing Howard De Walden’s redevelopment of One Marylebone High Street.

Property Type:

Office

Date on Market:

19/02/2026

London Retail to Rent - Marylebone, City of Westminster

The property comprises a building of masonry construction arranged over five floors offering retail accommodation on the lower levels and residential above. The property is located on Molyneux Street within London.

Date on Market:

16/02/2026

London Co-working to Rent - Marylebone, City of Westminster

Property Type:

Office

Date on Market:

10/02/2026

London Co-working to Rent - Marylebone, City of Westminster

The property comprises a terraced five floor traditional masonry built office building with ground and basement floor retail space. The site also fronts 9/11 Kendall Place. The property is located on the west side of Blandford Street close to its junction with Baker Street. The area also benefits from having access to good public transport as Bond Street Underground Station is nearby.

Property Type:

Office

Date on Market:

10/02/2026

London Co-working to Rent - Marylebone, City of Westminster

The property comprises a mid terraced building offering mixed use accommodation over five floors. The property comprises retail accommodation over basement and ground floor and office space above. The property is located on the north side of George Street midway between Baker Street and Marylebone High Street. The property offers good transport links with the numerous bus routes that pass along Baker Street as well as being within walking distance of Baker Street, Marble Arch and Bond Street underground stations.

Property Type:

Office

Date on Market:

10/02/2026

London Office to Rent - Marylebone, City of Westminster

One Cavendish Place is prominently located on the junction of Cavendish Place and Regent Street in the heart of the West End. The building is within quick walking distance of Oxford Circus (Victoria, Bakerloo and Central Lines) and Bond Street (Elizabeth, Central and Jubilee Lines) underground stations.

Date on Market:

28/01/2026

London Office to Rent - Marylebone, City of Westminster

46 Crawford Street is situated in the heart of Marylebone, close to Marylebone Road and Baker Street, offering excellent visibility and footfall. The area benefits from a mix of boutique shops, cafés, restaurants, and professional services, creating a vibrant yet affluent environment. Transport links are excellent, with Marylebone, Baker Street, and Edgware Road Underground stations within walking distance and frequent bus routes along Marylebone Road, providing easy access across Central London. This prime location combines strong commercial appeal, high-quality surroundings, and superb connectivity, ideal for a range of occupiers.

Date on Market:

15/01/2026

London Office to Rent - Marylebone, City of Westminster

This attractive period building is located on the east side of Baker Street, two minutes’ walk from Baker Street Station (Bakerloo, Jubilee, Metropolitan, Circle and Hammersmith & City Lines). The local area provides an excellent selection of bars, cafes, restaurants and shops.

Date on Market:

08/12/2025

London Office to Rent - Marylebone, City of Westminster

Located in the heart of the West End, 38 Seymour Street occupies a corner position in a tranquil area of south Marylebone, idyllically located in close proximity to Mayfair and Hyde Park. The transport connections are excellent with Marble Arch, Bond Street, and Baker Street underground stations in close walking distance.

Date on Market:

28/10/2025

London Retail to Rent - Marylebone, City of Westminster

Beauty and wellness rooms to rent in Marylebone. Selection of rooms available starting from £1355 per month. Brand new refurbished building. Ideal for aesthetics/laser beauty treatments etc. All bills included CQC readyBlank canvas - decorate your own to reflect your own brand. Air conditioned 24 Hour Access Flexible contracts Free wifi

Property Type:

Office

Date on Market:

06/11/2025

London Office to Rent - Marylebone, City of Westminster

55 Blandford Street is part of The George Blandford Estate, a family development in the same ownership for over 50 years – comprising individual shops, offices and residential. Occupiers include Gielly Green, Defune & the new Bellazul Restaurant & Bar. Close to both Baker Street & Bond Street Underground Stations. This Grade A development, behind a period façade, is part of the George Blandford Estate, sitting within a block by Blandford Street, George Street, Kendall Place & Manchester Street. Close to the Chiltern Firehouse Hotel – this unique building is in the heart of Marylebone Village, one of the most fashionable in London.

Date on Market:

02/07/2025

London Office to Rent - Marylebone, City of Westminster

Attractive office building situated in the heart of Marylebone.

Date on Market:

02/07/2025

London Office / Medical to Rent - Marylebone, City of Westminster

The accommodation is arranged over the lower ground floor and is held within an attractive period building. The building benefits from a concierge and waiting room on the ground floor. The lower ground floor is accessible via a passenger lift, and staircase. The unit is currently configured as a physiotherapist but would suit several medical consultations or rehabilitation uses. The space is currently configured with three treatment rooms and two rehabilitation gym studios. The space also includes changing rooms, showers, W.C. and a laundry room. The property benefits from mains gas, electric, water and drainage.

Property Type:

Office

Date on Market:

01/07/2025

London Office to Rent - Marylebone, City of Westminster

3 Mandeville Place is a beautifully refurbished Grade A office building in the heart of Marylebone. Exceptional local amenities with a first-class dining and leisure provision on St Christopher’s Place and outstanding retail on Marylebone High Street.

Date on Market:

15/04/2025

London Office to Rent - Marylebone, City of Westminster

The property is situated in the heart of Marylebone, on the East side of Wimpole Street close to the junction of Welbeck Way. Bond Street (Central and Jubilee lines),Oxford Circus (Victoria, Bakerloo and Central lines) and Baker Street (Metropolitan, Hammersmith & City, Bakerloo and Jubilee lines) Underground Stations are within short walking distance. The area benefits from an abundance of retailers, restaurants and bars.

Date on Market:

02/07/2025

London Office to Rent - Marylebone, City of Westminster

The property comprises a mixed-use building arranged over eight floors with retail space at basement and ground floor levels, office space on the first to fourth floors and residential space on the fifth and sixth floors. The property is located on the south side of Wigmore Street, between the junctions of Wimpole Street and Cavendish Square. Oxford Circus and Bond Street Underground Stations are both within easy walking distance.

Date on Market:

25/03/2025

London Co-working to Rent - Marylebone, City of Westminster

Located in the heart of Oxford Circus, just off the iconic Regent Street, this cost-effective property is easily accessed from Bond Street using both the underground and Elizabeth Line stations. The location of this office is fantastic for those wanting to explore the local amenities shops and restaurants the West End has to offer.

Property Type:

Office

Date on Market:

13/02/2025