Commercial Properties to Rent in Marylebone (London)

London Medical to Rent - Marylebone, City of Westminster

86 Harley Street offers period features, excellent natural light, a manned reception, and a shared waiting room. The Grade II listed building now offers a 588-square-foot medical suite on the first floor. This one-room suite has been newly redecorated. The Howard de Walden Estate sits at the heart of central London, one of the world’s best-connected cities – within easy reach of several airports, the St. Pancras Eurostar terminal, and numerous mainline and underground stations.

Property Type:

Office

Date on Market:

08/04/2025

London Office / Medical to Rent - Marylebone, City of Westminster

The 1,479-square-foot space comprises three consulting rooms and a kitchenette on the lower ground floor. There is also access to shared WCs and a shared waiting room on the ground floor. The Harley Street Health District is a community of Marylebone-based hospitals, clinics, and specialists, renowned for their outstanding patient care, pioneering treatments, and use of cutting-edge technologies. Combined with the convenience of Marylebone, this location places users among leading healthcare professionals.

Property Type:

Office

Date on Market:

08/04/2025

London Medical to Rent - Marylebone, City of Westminster

11 Devonshire Place has undergone a comprehensive refurbishment and now offers approximately 2,034 square feet of high-quality accommodation arranged across the ground and first floors. Finished to an excellent standard throughout, the building blends period character with modern functionality and has been thoughtfully configured to support professional medical use. The property benefits from seven well-proportioned consulting rooms, a kitchenette, two WCs, a shower facility, air conditioning, and a lift. An external extension further enhances the building’s flexibility, providing a self-contained staff area that could also serve as an ancillary or support space. The building is situated within the heart of the prestigious Harley Street Medical Area, the largest collection of private healthcare professionals in Europe. The area has been pioneering healthcare since the mid-19th century, and remains one of the world’s leading destinations for medical practitioners. Located in Marylebone, the surrounding neighbourhood offers a mix of medical, office, retail, and residential occupiers. Marylebone Village provides an array of restaurants, cafés, and shops, alongside hotels and gyms, while Regent’s Park, offering 395 acres of parkland and extensive leisure facilities, is just a short walk away. Connectivity is excellent, with Regent's Park and Great Portland Street Underground stations both within easy walking distance, and Marylebone Station also close by, ensuring convenient access for patients, staff, and visitors alike.

Property Type:

Office

Date on Market:

10/06/2024

London Office / Medical to Rent - Marylebone, City of Westminster

Property Type:

Office

Date on Market:

12/05/2026

London Medical to Rent - Marylebone, City of Westminster

Property Type:

Office

Date on Market:

09/03/2026

London Office, Office / Retail to Rent - Marylebone, City of Westminster

A Grade II listed entire office building is available in the heart of Marylebone opposite Wyndham Place and close to the junction of Seymour Place , just moments from both mainline and Underground stations. The property arranged over 5 floor and is offered as a whole or with retail to the ground and lower ground floor, with three additional floors of office space above.

Date on Market:

08/05/2026

London Retail to Rent - Marylebone, City of Westminster

Property Type:

Office

Date on Market:

28/04/2026

London Office to Rent - Marylebone, City of Westminster

The property comprises a self-contained five floored building with ground floor retail accommodation and office space on the upper floors.

Date on Market:

16/04/2026

London Office to Rent - Marylebone, City of Westminster

The property comprises a Grade II listed building which forms part of a Georgian style terrace of traditional masonry construction. The building is arranged as a basement and ground floor retail premises with self-contained office accommodation on the upper floors. The property is situated on the west side of Baker Street in between Bickenhall Street and York Street. Baker Street and Marylebone underground stations are within walking distance as well as numerous bus routes.

Date on Market:

30/03/2026

London Office to Rent - Marylebone, City of Westminster

51 Welbeck Street’s lower ground level provides a surprisingly bright and spacious office space for teams of 20+. Encompassing the entire floor, your new office is equipped with a large boardroom, three private offices, a storage cellar, kitchenette, plus room for over 15 open plan desks. Occupiers benefit from an on-site staffed reception, end of trip facilities, and a reputable address, surrounded by amazing local amenities. Your commute is simple too, with access to some of London’s major underground stations, all within a 5-15 minute walk.

Date on Market:

25/03/2026

London Office to Rent - Marylebone, City of Westminster

A mixed Residential/ Office building offering characterful loft style offices with excellent natural light close to Oxford Street.

Date on Market:

25/02/2026

London Office to Rent - Marylebone, City of Westminster

Bright and open plan offices in the heart of St Christopher's Place.

Date on Market:

25/02/2026

London Retail to Rent - Marylebone, City of Westminster

The property comprises a building of masonry construction arranged over five floors offering retail accommodation on the lower levels and residential above. The property is located on Molyneux Street within London.

Date on Market:

16/02/2026

London Co-working to Rent - Marylebone, City of Westminster

Property Type:

Office

Date on Market:

10/02/2026

London Co-working to Rent - Marylebone, City of Westminster

The property comprises a terraced five floor traditional masonry built office building with ground and basement floor retail space. The site also fronts 9/11 Kendall Place. The property is located on the west side of Blandford Street close to its junction with Baker Street. The area also benefits from having access to good public transport as Bond Street Underground Station is nearby.

Property Type:

Office

Date on Market:

10/02/2026

London Co-working to Rent - Marylebone, City of Westminster

The property comprises a mid terraced building offering mixed use accommodation over five floors. The property comprises retail accommodation over basement and ground floor and office space above. The property is located on the north side of George Street midway between Baker Street and Marylebone High Street. The property offers good transport links with the numerous bus routes that pass along Baker Street as well as being within walking distance of Baker Street, Marble Arch and Bond Street underground stations.

Property Type:

Office

Date on Market:

10/02/2026

London Office to Rent - Marylebone, City of Westminster

46 Crawford Street is situated in the heart of Marylebone, close to Marylebone Road and Baker Street, offering excellent visibility and footfall. The area benefits from a mix of boutique shops, cafés, restaurants, and professional services, creating a vibrant yet affluent environment. Transport links are excellent, with Marylebone, Baker Street, and Edgware Road Underground stations within walking distance and frequent bus routes along Marylebone Road, providing easy access across Central London. This prime location combines strong commercial appeal, high-quality surroundings, and superb connectivity, ideal for a range of occupiers.

Date on Market:

15/01/2026

London Office / Medical to Rent - Marylebone, City of Westminster

Situated at the junction of Harley Street and Cavendish Square, this medical space presents a prime opportunity for healthcare professionals.

Property Type:

Office

Date on Market:

07/01/2026

London Office to Rent - Marylebone, City of Westminster

This attractive period building is located on the east side of Baker Street, two minutes’ walk from Baker Street Station (Bakerloo, Jubilee, Metropolitan, Circle and Hammersmith & City Lines). The local area provides an excellent selection of bars, cafes, restaurants and shops.

Date on Market:

08/12/2025

London Office to Rent - Marylebone, City of Westminster

Located in the heart of Marylebone, 49 Welbeck Street provides the perfect backdrop for the future of your team. Fitted with desks for 5, a kitchenette, and a well-equipped 10 person boardroom, this space is ready for you to hit the ground running. 49 Welbeck Street is less than a ten minute walk from both Bond Street and Oxford Circus Stations, ensuring your team has a reliable and simple commute into the office. Take advantage of local amenities like The Marylebone Hotel, New Cavendish Street and the entire Marylebone Village, providing great food, entertainment, and seasonal events for you and your team to enjoy.

Date on Market:

26/11/2025

London Office to Rent - Marylebone, City of Westminster

The property comprises an office building of masonry construction arranged over basement, ground and five upper floors. The property is located on the east side of Duke Street, directly between Manchester Square to the north and Wigmore Street to the south. Baker Street, Bond Street and Marble Arch underground stations are all a short walk from the property.

Date on Market:

07/11/2025

London Office to Rent - Marylebone, City of Westminster

Located in the heart of the West End, 38 Seymour Street occupies a corner position in a tranquil area of south Marylebone, idyllically located in close proximity to Mayfair and Hyde Park. The transport connections are excellent with Marble Arch, Bond Street, and Baker Street underground stations in close walking distance.

Date on Market:

28/10/2025

London Retail to Rent - Marylebone, City of Westminster

Beauty and wellness rooms to rent in Marylebone. Selection of rooms available starting from £1355 per month. Brand new refurbished building. Ideal for aesthetics/laser beauty treatments etc. All bills included CQC readyBlank canvas - decorate your own to reflect your own brand. Air conditioned 24 Hour Access Flexible contracts Free wifi

Property Type:

Office

Date on Market:

06/11/2025